NEW ARTICLE! Clean 7’s Take on Weaving Ayurveda Into Your Detox
NEW ARTICLE! Clean 7’s Take on Weaving Ayurveda Into Your Detox

General questions, comments, and thoughtful ideas

Contact

Press inquiries, site info, sponsorships and sorts

Contact

To be featured on the site, or other editorial content ideas and suggestions:

Contact

For job inquiries, applications, internships, and more:

Contact
Be Well

WHAT EXACTLY is Autophagy?

What Exactly is Autophagy?
@DriOliver

When we think of a detox, we tend to think of the toxins we absorb from food and the atmosphere passing through our digestive tract. We think of our livers detoxing heavy metals, chemicals, and alcohol, losing weight from excess stored fat, and other systems of elimination. What doesn’t tend to surface at the top of our minds is cellular detox.

We exfoliate our skin to get rid of dead skin cells, but how do we “exfoliate” the inside of our bodies? We know we are always producing new cells as old cells die, so what happens to the old cells?

Say hello to autophagy, our old friend. Autophagy is, in the simplest of terms, the body’s way of ridding itself of these old, dead, or damaged cells. It’s our bodies’ natural housekeeping process.

In order to understand this on a straightforward yet granular level, we can break the word down into its parts. The latin word “auto” means self, and “phagy” means to eat — so in a sense, it is self-eating. Which brings us back to our original idea of detox: elimination. When we eliminate from our bodies, it’s not just food and waste from the environment, but also our own waste. That’s right — a huge part of poop is all our dead and damaged cells and pathogens that our body killed.

In order to understand this on a straightforward yet granular level, we can break the word down into its parts. The latin word “auto” means self, and “phagy” means to eat — so in a sense, it is self-eating. Which brings us back to our original idea of detox: elimination. When we eliminate from our bodies, it’s not just food and waste from the environment, but also our own waste. That’s right — a huge part of poop is all our dead and damaged cells and pathogens that our body killed.

And it’s not just damaged cells that we need to do away with, but metabolic waste as well. We accumulate metabolic waste in the brain daily, and part of deep, restorative sleep requires some level of autophagy. Misfolded proteins (aka deformed and essentially useless proteins) are removed, while damaged mitochondria and other cellular components (even intracellular pathogens, which are microorganisms that take over cells and multiply) are given the can during the process of autophagy.

Let’s revisit that notion of “self-eating.” Sounds a little scary, right? Kind of like something we don’t want to engage in? However, it’s actually a really beneficial part of maintaining longevity and fighting premature aging. It’s a part of self-regulating so that we can make way for fresh, new cells that are ready to function optimally.

Cleaning out the brain

Removing toxic protein build-up, namely in the brain, helps us clear out “brain junk.” This build-up creates a plaque-like substance that blocks neurons from communicating with each other, which is linked to neurodegenerative diseases like Alzeihmer’s, Parkinson’s, and even dementia.

Recycling amino acids

Amino acids are the building blocks of protein. We need them, and can’t always get an adequate amount from our food. Some proteins in our body are misfolded (aka malformed and non-functional), yet they still contain amino acids that we don’t want to waste. Autophagy helps to rid us of the malformed protein molecules while recycling, or saving, the amino acids for building new proteins.

Promoting cell regeneration

On a general level, autophagy is responsible for the regeneration of our cells into high functioning new cells, such as muscle stem cells.

While autophagy is a natural process, some of us don’t experience the benefits at the rate we need to based on poor lifestyle choices. Others want to boost their autophagic processes to improve their longevity and stave off aging as long as possible. So how can we boost our body’s natural autophagy?

Sleep

Our brains do most of their clean sweeping when we are getting deep, quality, restorative rest. This is when we clean that toxic protein plaque build-up out, and wash it away via the lymph — so don’t skimp on sleep.

Intermittent fasting (responsibly)

Because our body, in a way, is “self-eating” during autophagy, we can trigger this when we fast. On the most basic level, we are forcing our bodies into utilizing other waste stores for energy, and can kick start the process.

NAC supplementation

Studies show that N-acetylcysteine (NAC) supplementation is pro-autophagic, reducing cell injury and more rapidly sweeping our damaged cells out.

Green tea

It’s been shown that the powerful polyphenols in green tea can induce autophagy. It’s also anti-photoaging, improves our resistance to stress, and is neuroprotective. Drink your matcha, honey.